Photoreceptors are specialized cells in the eye that convert light energy into neural signals. Several diseases that cause irreversible vision loss, including age-related macular degeneration, ...
(A) CuN is formed by self-assembly of Cu²⁺ and NLG919 via Cu-N coordination bonds, with chemotherapeutic agents (e.g., β-lapachone) encapsulated through hydrophobic interactions. (B) Lap@CuN passively ...
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare. Thus, CDK4/6 ...
Marcela Maus, MD, PhD, director of the Cellular Immunotherapy Program and the Paula J. O'Keeffe Endowed Chair of the Mass General Cancer Center, is senior author and Stefanie Bailey, PhD, Hana Takei, ...
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