Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

Northwestern Medicine scientists led by Joseph Bass, MD, Ph.D., the Charles F. Kettering Professor of Endocrinology and ...

Something happens when a rat starts running. Not just the obvious things, the faster heart, the warming muscles, the rhythmic percussion of paws against the wheel. Something quieter. Something that ...

Inflammatory osteolysis is a condition involving progressive bone tissue destruction and is observed in many well-known ...

Inflammation of bones is a characteristic of disorders like apical periodontitis. Researchers have found that copper-mediated ...

Preclinical research across multiple cancer types now shows that the NAD+ salvage pathway, the same biological mechanism targeted by popular anti-aging supplements like nicotinamide mononucleotide ...

Hepatobiliary and pancreatic tumors represent a critical area of oncological research due to their aggressive nature, limited ...

NAEs are lipid-based endogenous signaling molecules that are produced by combining long-chain fatty acids with ethanolamine. Collectively, NAEs include both endocannabinoids and structurally related ...

Exposure to a diet heavy in fats and sugars during early development primes the brain to overreact to unhealthy foods in ...

Voluntary exercise reshapes gut microbiota and tryptophan metabolism, with consequences for the hippocampus, the ...