The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...

It's known as biology's central dogma: All living organisms' genetic information is stored in DNA, which is transcribed into RNA, which is translated into proteins that perform nearly all essential ...

Nonsense-mediated mRNA decay (NMD) is one of the most important processes in our cells to ensure that no faulty or incomplete proteins are produced. Scientists have now identified a central mechanism ...

Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein ...

The demand for complex therapeutic proteins, is rapidly accelerating, with the bispecific market alone projected to grow to $50B by 2030. While these atypical molecules offer transformative clinical ...

Scientists have identified a critical breakdown in the cellular machinery that produces proteins in aging brains.